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Add DeSeq2 support (Read 736 times)
Aug 6th, 2019 at 4:28pm

Mike Shelk   Offline
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Posts: 4

Currently UGENE uses cuffdiff for differential expression analysis. Cuffdiff is outdated and produces more false positives than many other tools. I think many people will be glad if you add a more modern tool for the differential expression analysis, for example DeSeq2. A comparison can be found in the paper "How many biological replicates are needed in an RNA-seq experiment and which differential expression tool should you use?" (2016).
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Reply #1 - Aug 12th, 2019 at 1:41pm

Olga Golosova   Offline
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Posts: 338
Hi Mike!

Thank you for the feedback!

We plan to integrate DeSeq2, however for now we can't specify the exact deadlines when this will be done.
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Reply #2 - Dec 28th, 2020 at 11:36pm

alfredlan   Offline
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Great! DeSeq2 is a really helpful tool. It would improve the performance of UGENE. That was a valuable suggestion.
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