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Add a tool for multiple alignment cleaning (Read 77 times)
Aug 15th, 2019 at 5:25pm

Mike Shelk   Offline
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There are several programs that can automatically detect poorly aligned regions in a multiple alignment and remove them. For example, Gblocks and TrimAL are popular with 6000 citations and 2000 citations respectively. I and, I think, many other users will be glad if you incorporate one of these tools into UGENE.
Also, thank you for your job. Donated 10 euros today.
 
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Reply #1 - Aug 15th, 2019 at 6:36pm

Olga Golosova   Offline
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Thank you for the feedback! We'll consider integrating these tools.

You've also recently proposed to integrate DESeq2. Do you use it and these two tools for different projects or for the same one? I'd like to understand the analysis workflow in general...

Quote:
Also, thank you for your job. Donated 10 euros today.

Received! Thank you very much!
 
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Reply #2 - Aug 15th, 2019 at 6:49pm

Mike Shelk   Offline
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This is for two different projects. Gblocks is good for an alignment cleaning prior to a phylogenetic tree building. I need it for a phylogenetic study. DESeq2 is for differential expression analysis, which is a part of another project.
 
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Reply #3 - Aug 15th, 2019 at 6:50pm

Olga Golosova   Offline
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Ok, I see, that's what I thought.
 
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