Align with T-Coffee Element

T-Coffee is a multiple sequence alignment package.

T-Coffee is used as an external tool from UGENE and it must be installed on your system. To learn more about the external tools, please read the main UGENE User Manual.

Element type: tcoffee

Parameters

ParameterDescriptionDefault valueParameter in Workflow FileType
Gap extension penaltyGap extension penalty. Positive values reward gaps and prevent the alignment of unrelated segments.0gap-ext-penaltynumeric
Gap open penaltyGap open penalty. Must be negative, the best matches get a score of 1000.-50gap-open-penaltynumeric
Max iterationNumber of iterations on the progressive alignment. 0 - no iteration, -1 - Nseq iterations.0iterations-max-numnumeric
Tool path (required)Path to the ClustalW tool. The default path can be set in the UGENE Application Settings.defaultpathstring
Temporary directoryDirectory to store temporary files.defaulttemp-dirstring

Input/Output Ports

The element has 1 input port:

Name in GUI: Input MSA
Name in Workflow File: in-msa
Slots:

Slot In GUISlot in Workflow FileType
MSAmsamsa

And 1 output port:

Name in GUI: Multiple sequence alignment
Name in Workflow File: out-msa
Slots:

Slot In GUISlot in Workflow FileType
MSAmsamsa